Transdermal Research Program

Transdermal Research Program

Transdermal routes of medication delivery are becoming increasingly accepted due to the lower incidence of side effects and convenience. At AMS we are able to deliver three different transdermal programs that your office can offer to your patients to help with pain, allergy or scar treatment.

These programs are a observational research study to determine patient acceptance and efficacy. The study involves recruitment of suitable patients into the program(s) your office selects. The patient will first complete a survey to determine eligibility and then regular surveys to determine efficacy.

The physician is reimbursed for their time involvement in the study dependent on the number of patients that complete a survey each month. A research coordinator is provided to the office when commencing the program to ensure you receive full support to get the program running.

The transdermal research approach incorporates comparative effectiveness research (CER) methodologies. This form of research looks at different strategies and interventions to monitor and treat pain, allergy and scars. The studies are IRB approved and can be quickly and easily integrated into your office practice.

Allergy

Alergy

Allergy is a popular program and one that is now available to a variety of practice types. The study program is a large scale IRB approved study that evaluates the effectiveness of a topical antihistamine formulation as a replacement for oral antihistamines and also a topical immunotherapy to replace needle based antigen treatment.

Currently seasonal and perennial allergies are among the most underdiagnosed, undertreated, chronic allergic condition which affects approximately 10 to 20% of the US population.

Millions of Americans are suffering from allergies that may be undiagnosed or not treated. This research program enables primary care providers, such as Family or Internal Medicine to offer allergy treatment without the need to refer out or be involved in mixing serums.

Pediatric offices are able to offer allergy treatment to patients 6 and over using a more accepted form of treatment – topical therapy. Allergy has been difficult to treat in children due to the fear factor associated with needles and the constant need to return to the physician office for injections.

This solution can also work well for Allergy and Asthma practices that typically see a high dropout rate for in office immunotherapy due to the inconvenience factor and slow improvement in symptoms. Offering a topical alternate enables an allergy practice to re-engage patients who may previously have dropped out of a subcutaneous program. This also helps safeguard declining reimbursements as many insurers continue to scrutinise immunotherapy costs.

Outcomes of the trial are being presented at conferences as the results become available.

At AMS we have a range of allergy programs designed to meet the needs of your patient base and our most recent addition is the IRB approved transdermal Allergy program. Talk to your consultant to determine the best program for your practice needs.

Pain

Joint Image

Transdermal pain treatment has the advantage of applying a cream at the site of the pain. Transdermal treatment also provides an alternate treatment for the high number of patients suffering from chronic pain. As many as 40% of patients treated for chronic pain do not achieve pain relief which can severely impact quality of life and functionality.

Many pain medications can have a range of associated side effects. Applied transdermally, pain creams produce fewer systemic effects and have a lower risk of drug to drug interactions. Topical therapy has a high patient acceptance with 95% of patients satisfied with this form of therapy. The creams are often used as an adjunct to other therapies to help patients attain a higher level of pain control.

Topical treatments can mean the reduction of dosage or use of other oral therapies which can lower the likelihood of medication misadventures.

Findings from the research to date include:

  • Reduced pain severity for patients with neuropathic and musculoskeletal pain
  • Reduced pain interference with general activity, mood, sleep and life enjoyment
  • Reduced number of primary pain complaints for arthritis, neuropathy or radiculopathy
  • Reduced use of over the counter medications, anti inflammatories and opioid analgesics
  • 95% of patients were satisfied with the topical analgesic which was safe and well tolerated.
Pain Images

This study uses the Brief Pain Inventory as a validated tool for assessing the severity of pain and the impact on daily activities of the patients with different chronic pain causalities

Many practice types can get involved in this program including Pain, Orthopedic, Family and Internal medicine and Neurology. To find out more talk to your consultant.

Scar

A research trial is also available for topical treatment for scar or burn tissue. Scars are often considered to be an aesthetic issue but also can cause tenderness, itching, pain and deformity. This can further result in psychological conditions such as depression, reduced self esteem and anxiety.

Scar Images

The research trial uses validated scales for scar assessment and reduction in pain scores. Findings to date include

  • Reduction in scar size reported in 69% of patients
  • Reduced itching
  • Reduction in scar/burn interference with general activity, mood, sleep and life enjoyment
  • Reduced use of pain medications by 69%
  • Most patients believed that the scar had improved in appearance and were safe and well tolerated with no serious adverse effects.

How Does It Work?

genetic counselling

Work with your consultant to determine which program(s) can work for your practice. They can provide you with a wide range of study information including proforma surveys, protocols and formularies. The sign up process is done electronically with training then provided to you and your staff. The initial step is completing a practice analysis. The office can be up and running with the program within a short period of time once you decide which trials to proceed with.

Your time as an investigator physician will be compensated at a fair market rate and will help to ensure the viability of your practice and satisfaction of your patients. Compensation begins at 10 surveys per month with a cap of 100. A research coordinator will assist you in getting started. This can add significant revenue to your practice and you have the ability to add three different programs should you choose.

How Do I Get Started?

Once the appropriate program has been identified your consultant can provide you a paper copy of the agreements but final agreements will be submitted electronically to ensure all the appropriate documentation is completed. The programs will then begin to generate revenue for your office after each month that sufficient surveys have been submitted.

happy patient and doc

1) Complete a Practice Analysis and Demographic

2) Submit electronic documentation when prompted to become an investigator

3) Training is performed and a Research Coordinator provided to the office to get started

4) Identify suitable patients with the supplied surveys

5) Recruit patients into the study

6) Initial surveys take about 5 to 8 minutes to complete

7) Submit surveys

8) Compensation received for investigator time

In Summary

The research based programs enable your office to help your patients attain relief from several common and difficult to treat conditions. Your office can choose from up to three different programs and be enrolled in them collectively or individually to maximize revenues. The research studies are all IRB approved and position your office as a investigator for these important observational trials. Your office receives vital support in commencing the program to ensure its success. Your patients will benefit from the improved symptom control and convenience of transdermal application. Talk to your consultant to determine the best programs for your office.