Pharmacogenetic Testing

DNA PHARMACOGENETIC TESTING

Discover the New Breakthrough in Prescribing Efficacy

One simple test to deliver effective treatments and eliminate adverse drug reactions.

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Until recently, dosing and prescribing has been both an art and a system of trial and error. Now, developments in the field of genetic testing have made finding the right dose and the right medication for the patient a science. The 5th leading cause of death in America today is
pharmaceutical complications – isn’t it time we lowered that number?

Using the patient’s own DNA, Pharmacogenetic Testing maps the CYP450 system and its enzymes, giving the clinician the ability to choose and tailor medication choices specific to that patient’s genetic profile. The CYP450 enzyme system is a key pathway for drug metabolism, particularly with regard to drug interactions. Approximately 92% of all medications are metabolized through the CYP450 system.

Ancillary Medical Solutions and Life Genomics have partnered to offer Pharmacogenetic testing at no cost to the provider and in a format that is Medicare reimbursable. The process is simple – a quick cheek swab for your patient and in under 10 business days your office will
have a full, easy-to-read report on their genetic make-up with dosing recommendations and warnings from the top genetic testing specialists in the world.

“The use of genotyping to make therapeutic recommendations to improve therapeutic efficacy and to prevent toxicity in patients is promising and clinically relevant.”

– Drug Metabolism Reviews

Advantages for Patients and Physicians

  • Ability to make more informed medical decisions
  • Higher probability of desired outcomes thanks to better targeted therapies
  • Reduced probability of negative side effects
  • Focus on prevention and prediction of disease rather than reaction to it
  • Earlier disease intervention than has been possible in the past
  • Peace of mind about side effects
  • Decreased chance of hospitalization

The Right Drug for The Right Patient at The Right Dosage

Therapeutic Classes of Drugs
Utilizing the CYP450 System

ADHD Opioids
Antiarrhythmic Statins
Antidepressants Aspirin
SSRI/SNRI Other Analgesics
Antidepressants Urinary Incontinence
Tricyclic Treatment
Antidiabetics HIV
Antiemetics Beta Blockers
Antiepileptic Calcium Channel
Antihyperlitemic Agents Blockers
Antiplatelet Benzodiazepine
Anticoagulants Antiviral Agents
Antipsychotics Drugs of Abuse
Anxiety/Insomnia Hormones/Steroids
Acid related disorders Antibiotics/Antifungals
Muscle Relaxants Chemotherapeutic

How Many of Your Patients Could Benefit From a Better Understanding of the Ways These Drugs Work In Their Systems?

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Start-Up and Implementation

How Do I Get Started?

No Application Needed

When it comes to turnkey solutions it doesn’t get much easier than this. Simply inform your Certified Ancillary Consultant that you would like to try out the Pharmacogenetic Testing system and they will ensure you get a set of swabs and pre-paid envelopes. As your patients come to see you, offer them a quick cheek swab test and send it off in the mail!

Testing Days

Providers have had the most success with Pharmacogenetic testing by scheduling one or two days out of the month for patients to drop in at their own convenience for a cheek swab. By sending these tests out as a group you will receive reports for a larger portion of your patients before they come in with a complaint or complication.

CYP450 System

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92% of all medications are metabolized using this pathway

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1) Supply your AMS Certified Ancillary Consultant with your practice address and NPI #.

2) Receive your testing kits, free of charge, in the mail or from your AMS Consultant.

3) Fill out the patient information sheets, swab their cheek, and send off the swab in the pre-paid envelopes.

4) In 10 business days or less your clinic will receive a detailed report on your patient’s specific genetic make-up.

5) Begin prescribing medications based on scientific information and create better patient outcomes.

Facts & Figures

Patient Metabolizer Profiles

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The Poor Metabolizer:

A patient whose body, although they have a high concentration of the medication in their system, does not metabolize it efficiently and they have various side effects.

The Normal Metabolizer:

The normal metabolizer is someone who reacts as expected and gets the intended benefit of the medication with minimal side effects.

The Hyper Metabolizer:

The patient who is a hyper metabolizer will display less than optimal clinical benefits from the prescribed medication. This patient metabolizes and clears the drug quicker than normal, resulting in lower/suboptimal therapeutic drug levels.

Use Pharmacogenomics to Prevent Drug Reactions

Several drugs can cause severe or life-threatening reactions in patients who have certain variations in their genes. Knowing about patients’ genetic variations can help physicians avoid drugs that may cause these adverse reactions.

Pharmacogenomics is the identification of individual genetic (DNA) differences in patients which cause varied responses to a single drug. The CYP450 enzyme system is a key pathway for drug metabolism, particularly with regard to drug interactions. Many drug interactions are
a result of inhibition or induction of the CYP450 enzymes.

Using a patient’s own DNA, Pharmacogenetic Testing uniquely maps the CYP450 system and its enzymes, giving the clinician the ability to choose and tailor medication to that patient’s very specific genetic make-up.

The Bottom Line

This service is entirely free to your practice and is provided as an informational service to benefit your patients. Prescribe with confidence and watch your outcomes improve.